The answer is Paul and Constantine.
John the Baptist is a significant figure in Christianity, known for baptizing Jesus and preaching about repentance. However, he is not considered a "founder" of Christianity. His role was more of a precursor to Jesus' ministry rather than a foundational figure in the establishment of the Christian faith.
Paul, also known as the Apostle Paul, is often considered one of the founders of Christianity due to his extensive missionary work and his role in spreading the teachings of Jesus to the Gentile world. His epistles form a significant portion of the New Testament, and his theological contributions helped shape early Christian doctrine.
Constantine the Great, the Roman Emperor, played a crucial role in the establishment of Christianity as a major religion within the Roman Empire. By issuing the Edict of Milan in 313 AD, he legalized Christianity and ended the persecution of Christians. His support for the Church and the Council of Nicaea in 325 AD were pivotal in the development and spread of Christianity.
Martin Luther was a key figure in the Protestant Reformation, which occurred much later in the 16th century. While he significantly impacted Christianity by challenging the practices of the Catholic Church and initiating Protestantism, he is not considered a "founder" of Christianity itself.
John Calvin was another influential figure in the Protestant Reformation, known for his role in developing Calvinism. Like Martin Luther, his contributions were significant in the context of the Reformation but not in the founding of Christianity.
Our Lady of Guadalupe is a title for the Virgin Mary associated with a series of apparitions in Mexico in the 16th century. While she is an important religious symbol, particularly in Latin America, she is not considered a founder of Christianity.