The answer is A: Frankenstein (book).
Explanation for each option:
A. Frankenstein (book): This is the correct answer. Mary Shelley's novel "Frankenstein," published in 1818, is one of the earliest and most famous works of literature to explore the theme of science overstepping its natural boundaries. The story revolves around Victor Frankenstein, a scientist who creates a living being from dead tissue, only to face dire consequences. The novel raises questions about the ethical limits of scientific experimentation and the responsibilities of creators towards their creations.
B. The Monster of Frankenstein (movie): While this movie is based on Mary Shelley's novel, it is not the original work that first tackled the idea of science overstepping its natural boundaries. The original novel predates the movie adaptations.
C. The Boys from Brazil (movie): This 1978 film deals with the theme of cloning and the ethical implications of genetic manipulation, but it is not one of the first works to address these issues. It came much later than Mary Shelley's "Frankenstein."
D. The Bionic Woman (TV show): This television show, which aired in the 1970s, focuses on a woman who is given bionic implants after a near-fatal accident. While it does explore themes of scientific advancement and its impact on humanity, it is not one of the earliest works to tackle the idea of science overstepping its natural boundaries.
In summary, Mary Shelley's "Frankenstein" is widely recognized as one of the first artistic works to delve into the ethical and moral questions surrounding scientific experimentation and its potential to overreach natural limits.