The answer is Net profit margin.
Gross profit margin measures the difference between sales and the cost of goods sold (COGS). It does not account for other operating expenses, taxes, or interest, so it does not determine the overall profit from all sales.
Net profit margin is used to determine the overall profit obtained from all sales during the period. It takes into account all expenses, including operating expenses, interest, and taxes, providing a comprehensive view of profitability.
Operating profit margin measures the profit a company makes from its operations, excluding non-operating income and expenses. It does not account for taxes and interest, so it does not reflect the overall profit.
Return on assets (ROA) measures how efficiently a company uses its assets to generate profit. It is not specifically used to determine the overall profit from sales.