Questions: Which parts of the T-cell antigen receptor account for the diversity of antigens that T-cells can recognize? a.) The amino acid sequences of the variable domains of the beta chains only. b.) The amino acid sequences of the variable domains of both the alpha and beta chains. c.) The amino acid sequences of the variable domains of the alpha chains and the constant domains of both alpha and beta chains. d.) The amino acid sequences of the variable domains of the alpha chains only.

Which parts of the T-cell antigen receptor account for the diversity of antigens that T-cells can recognize?
a.) The amino acid sequences of the variable domains of the beta chains only.
b.) The amino acid sequences of the variable domains of both the alpha and beta chains.
c.) The amino acid sequences of the variable domains of the alpha chains and the constant domains of both alpha and beta chains.
d.) The amino acid sequences of the variable domains of the alpha chains only.

Transcript text: Which parts of the T-cell antigen receptor account for the diversity of antigens that T-cells can recognize? a.) The amino acid sequences of the variable domains of the beta chains only. b.) The amino acid sequences of the variable domains of both the alpha and beta chains. c.) The amino acid sequences of the variable domains of the alpha chains and the constant domains of both alpha and beta chains. d.) The amino acid sequences of the variable domains of the alpha chains only.

Solution

The answer is the second one (or B): the amino acid sequences of the variable domains of both the alpha and beta chains.

Explanation for each option:

a.) The amino acid sequences of the variable domains of the beta chains only.

This option is incorrect because the diversity of antigens that T-cells can recognize is not solely due to the beta chains. Both alpha and beta chains contribute to the diversity.

b.) The amino acid sequences of the variable domains of both the alpha and beta chains.

This option is correct. The variable domains of both the alpha and beta chains of the T-cell receptor (TCR) are responsible for the diversity of antigens that T-cells can recognize. The combination of different variable regions in these chains allows for a vast array of antigen recognition.

c.) The amino acid sequences of the variable domains of the alpha chains and the constant domains of both alpha and beta chains.

This option is incorrect because the constant domains do not contribute to the diversity of antigen recognition. The diversity is primarily due to the variable domains.

d.) The amino acid sequences of the variable domains of the alpha chains only.

This option is incorrect because, similar to option a, it does not account for the contribution of the beta chains. Both alpha and beta chains are necessary for the full diversity of antigen recognition.

Summary: The diversity of antigens that T-cells can recognize is due to the amino acid sequences of the variable domains of both the alpha and beta chains of the T-cell antigen receptor.

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