Questions: If we used normal mouse mAbs to treat human disease, multiple doses would cause the patient to respond with against the mouse antibodies.

If we used normal mouse mAbs to treat human disease, multiple doses would cause the patient to respond with against the mouse antibodies.

Transcript text: If we used normal mouse mAbs to treat human disease, multiple doses would cause the patient to respond with $\qquad$ against the mouse antibodies.

Solution

The answer is: an immune response

Explanation: When normal mouse monoclonal antibodies (mAbs) are used to treat human diseases, the human immune system recognizes these mouse antibodies as foreign proteins. As a result, the patient's immune system mounts an immune response against the mouse antibodies. This immune response can lead to the production of human anti-mouse antibodies (HAMA), which can neutralize the therapeutic effects of the mouse mAbs and potentially cause adverse reactions in the patient.

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