Questions: Question 10 2 pts Experimental evidence using germ free animals has demonstrated "phenotype transfer" of human disease symptoms using only gut microbes. In these experiments, gut microbiome from people are transferred into the gut of germ free mice, and after colonization, the mice exhibit symptoms of the disease. This indicates that: Conditions like colon cancer appear hereditary because of transfer of microbes to offspring during delivery Gut microbes are the only cause of conditions like obesity, autism spectrum disorder, and colon cancer Gut microbes contribute to presentation of complex diseases thought to have no microbial cause 'Complex human disease like obesity are completely curable using microbiome interventions

Question 10
2 pts

Experimental evidence using germ free animals has demonstrated "phenotype transfer" of human disease symptoms using only gut microbes. In these experiments, gut microbiome from people are transferred into the gut of germ free mice, and after colonization, the mice exhibit symptoms of the disease. This indicates that:
Conditions like colon cancer appear hereditary because of transfer of microbes to offspring during delivery
Gut microbes are the only cause of conditions like obesity, autism spectrum disorder, and colon cancer
Gut microbes contribute to presentation of complex diseases thought to have no microbial cause
'Complex human disease like obesity are completely curable using microbiome interventions

Transcript text: Question 10 2 pts Experimental evidence using germ free animals has demonstrated "phenotype transfer" of human disease symptoms using only gut microbes. In these experiments, gut microbiome from people are transferred into the gut of germ free mice, and after colonization, the mice exhibit symptoms of the disease. This indicates that: Conditions like colon cancer appear hereditary because of transfer of microbes to offspring during delivery Gut microbes are the only cause of conditions like obesity, autism spectrum disorder, and colon cancer Gut microbes contribute to presentation of complex diseases thought to have no microbial cause 'Complex human disease like obesity are completely curable using microbiome interventions

Solution

The answer is the third one: Gut microbes contribute to presentation of complex diseases thought to have no microbial cause.

Explanation for each option:

Conditions like colon cancer appear hereditary because of transfer of microbes to offspring during delivery: This option suggests that the hereditary appearance of conditions like colon cancer is solely due to the transfer of microbes during delivery. While gut microbes can be transferred during birth, this does not fully explain the hereditary nature of such diseases, which also involve genetic factors.
Gut microbes are the only cause of conditions like obesity, autism spectrum disorder, and colon cancer: This option is incorrect because it overstates the role of gut microbes. While gut microbes can contribute to these conditions, they are not the only cause. These diseases are multifactorial, involving genetic, environmental, and other biological factors.
Gut microbes contribute to presentation of complex diseases thought to have no microbial cause: This option is correct. The experimental evidence shows that gut microbes can influence the presentation of complex diseases, indicating that microbes play a role in conditions previously not thought to have a microbial cause.
Complex human disease like obesity are completely curable using microbiome interventions: This option is incorrect because it overstates the potential of microbiome interventions. While such interventions may help manage or alleviate symptoms, they are unlikely to completely cure complex diseases like obesity, which involve multiple factors.

Summary: The experimental evidence indicates that gut microbes contribute to the presentation of complex diseases thought to have no microbial cause.

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