The answer is American Revolution.
The Monroe Doctrine was a policy declared in 1823, long after the First Great Awakening, which occurred in the 1730s and 1740s. The Monroe Doctrine was primarily concerned with opposing European colonialism in the Americas and does not have a direct connection to the social foundations laid by the First Great Awakening.
While the First Great Awakening did influence American society, its primary impact was on religious and social structures rather than directly encouraging westward expansion. The movement west was more significantly driven by later events and policies, such as the Louisiana Purchase and Manifest Destiny.
The First Great Awakening had a significant impact on the American colonies by promoting ideas of individualism, challenging established religious and governmental authority, and encouraging a sense of shared American identity. These ideas contributed to the ideological underpinnings of the American Revolution, making this the most relevant connection.
The French and Indian War (1754-1763) was a conflict between British and French forces in North America, which occurred after the First Great Awakening. While the war did have significant consequences for the American colonies, it was not directly influenced by the social changes brought about by the First Great Awakening.