The nonsteroid hormone molecule is the small, blue sphere outside the cell. It is labeled in the diagram.
The membrane-bound receptor molecule is the purple structure embedded in the cell membrane. It is labeled in the diagram.
The hormone-receptor complex is formed when the nonsteroid hormone molecule binds to the membrane-bound receptor molecule. It is not directly labeled in the diagram but is represented by the combined structure of the hormone and receptor.
The G protein is the small, light purple oval attached to the inner side of the cell membrane, near the receptor. It is labeled in the diagram.
The active protein is the G protein after it has been activated by the hormone-receptor complex. It is the same structure as the G protein but is typically depicted in a different color or shape to indicate its active state. Here it is represented by the light purple oval moving towards adenylate cyclase.
Adenylate cyclase is the enzyme embedded in the cell membrane, shown as a pink structure. It is activated by the active G protein.
ATP is the small, orange circle near adenylate cyclase. It is the substrate for adenylate cyclase.
cAMP is the small, yellow orange circle produced by adenylate cyclase from ATP. It acts as a second messenger inside the cell.
The inactive protein is the purple sphere within the cytoplasm. It is labeled as the inactive protein.
Cellular changes are the final result of the signaling pathway, initiated by the binding of the nonsteroid hormone. It is the activated protein, represented by the inactive protein after interaction with cAMP. It is labeled in the diagram.
- Nonsteroid hormone molecule: Blue sphere outside the cell
- Membrane-bound receptor molecule: Purple structure in the cell membrane
- Hormone-receptor complex: Combined hormone and receptor
- G protein: Light purple oval near receptor (and activated G protein moving away)
- Active protein: Activated G protein
- Adenylate cyclase: Pink structure in the membrane
- ATP: Orange circles near adenylate cyclase
- cAMP: Yellow orange circles
- Inactive protein: Purple sphere inside the cell
- Cellular changes: Activated protein (previously inactive protein) after interaction with cAMP.