To solve the given expression, we need to follow the order of operations, also known as PEMDAS (Parentheses, Exponents, Multiplication and Division (from left to right), Addition and Subtraction (from left to right)). We will start by solving the innermost parentheses and work our way outwards.
Primero, evaluamos la expresión más interna:
\[
-2 + 5 = 3
\]
Luego, calculamos la multiplicación:
\[
4 \cdot 3 = 12
\]
A continuación, sumamos dentro de los corchetes:
\[
7 + 12 = 19
\]
Ahora, evaluamos la expresión en los corchetes exteriores:
\[
-3 - 19 = -22
\]
Finalmente, sumamos y restamos los términos restantes:
\[
-2 + (-22) - 4 = -28
\]
\(\boxed{-28}\)