Questions: Which of the following is a therapeutic action of raloxifene? Blocks the effects of estrogen on endometrial tissue Mimics the effects of estrogen on bone tissue Stimulates secretion of parathyroid hormone Stimulates menstruation

Which of the following is a therapeutic action of raloxifene? Blocks the effects of estrogen on endometrial tissue Mimics the effects of estrogen on bone tissue Stimulates secretion of parathyroid hormone Stimulates menstruation
Transcript text: Which of the following is a therapeutic action of raloxifene? Blocks the effects of estrogen on endometrial tissue Mimics the effects of estrogen on bone tissue Stimulates secretion of parathyroid hormone Stimulates menstruation
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Solution

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The answer is the second one: Mimics the effects of estrogen on bone tissue.

Explanation for each option:

  1. Blocks the effects of estrogen on endometrial tissue: This is incorrect. Raloxifene does not block the effects of estrogen on endometrial tissue. Instead, it acts as an estrogen antagonist in breast and uterine tissues, which helps reduce the risk of estrogen-dependent cancers.

  2. Mimics the effects of estrogen on bone tissue: This is correct. Raloxifene is a selective estrogen receptor modulator (SERM) that mimics the effects of estrogen on bone tissue. It helps to maintain bone density and reduce the risk of fractures in postmenopausal women.

  3. Stimulates secretion of parathyroid hormone: This is incorrect. Raloxifene does not stimulate the secretion of parathyroid hormone. Its primary action is on estrogen receptors, not on the parathyroid glands.

  4. Stimulates menstruation: This is incorrect. Raloxifene does not stimulate menstruation. It is typically used in postmenopausal women and does not have an effect on the menstrual cycle.

Summary: Raloxifene's therapeutic action includes mimicking the effects of estrogen on bone tissue, which helps in maintaining bone density and reducing the risk of fractures in postmenopausal women.

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