To simplify the expression \(2 \sqrt{27} - 3 \sqrt{108} - 8 \sqrt{108}\), we first simplify each square root term. We express the numbers under the square roots as products of perfect squares and simplify. Then, we combine like terms.
Step 1: Simplifying Each Term
We start with the expression \(2 \sqrt{27} - 3 \sqrt{108} - 8 \sqrt{108}\). We simplify each square root term:
Now we substitute the simplified terms back into the expression:
\[
6 \sqrt{3} - 18 \sqrt{3} - 48 \sqrt{3}
\]
Combining these gives:
\[
(6 - 18 - 48) \sqrt{3} = -60 \sqrt{3}
\]
Final Answer
The simplified expression is \(\boxed{-60 \sqrt{3}}\).