Questions: Which of these would be found on the surface of every B cell, T cell and pancreatic cell? MHC class II molecules MHC class I molecules CD4 Both MHC class i and class II molecules A rearranged antigen-specific receptor

Which of these would be found on the surface of every B cell, T cell and pancreatic cell? MHC class II molecules MHC class I molecules CD4 Both MHC class i and class II molecules A rearranged antigen-specific receptor

Transcript text: Which of these would be found on the surface of every B cell, T cell and pancreatic cell? MHC class II molecules MHC class I molecules CD4 Both MHC class $i$ and class II molecules A rearranged antigen-specific receptor

Solution

The answer is: MHC class I molecules.

Explanation for each option:

MHC class II molecules: These are typically found on the surface of antigen-presenting cells (APCs) such as dendritic cells, macrophages, and B cells, but not on all cells like T cells and pancreatic cells.
MHC class I molecules: These are found on the surface of almost all nucleated cells, including B cells, T cells, and pancreatic cells. They play a crucial role in presenting endogenous antigens to cytotoxic T cells.
CD4: This is a co-receptor found on the surface of helper T cells, but not on B cells or pancreatic cells.
Both MHC class I and class II molecules: This is incorrect because not all cells express both classes. MHC class II is limited to certain immune cells, while MHC class I is found on almost all nucleated cells.
A rearranged antigen-specific receptor: This is specific to B cells (B cell receptors) and T cells (T cell receptors), but not found on pancreatic cells.

Summary: MHC class I molecules are found on the surface of every B cell, T cell, and pancreatic cell.

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