Questions: Select the correct order of events that occur during the embryonic and fetal stages of the long bone development observed during the audio tour: - Formation of a bone collar, formation of bone model made of hyaline cartilage, formation of small cavities and invasion of blood vessels, replacement of cartilage by bone in the diaphysis - Formation of bone model made of hyaline cartilage, formation of small cavities and invasion of blood vessels, formation of a bone collar, replacement of cartilage by bone in the diaphysis. - Formation of bone model made of hyaline cartilage, formation of a bone collar, formation of small cavities and invasion of blood vessels, replacement of cartilage by bone in the proximal and distal epiphyses - Formation of bone model made of hyaline cartilage, formation of a bone collar, formation of small cavities and invasion of blood vessels, replacement of cartilage by bone in the diaphysis.

The answer is the fourth one: Formation of bone model made of hyaline cartilage, formation of a bone collar, formation of small cavities and invasion of blood vessels, replacement of cartilage by bone in the diaphysis.

Explanation for each option:

1. Formation of a bone collar, formation of bone model made of hyaline cartilage, formation of small cavities and invasion of blood vessels, replacement of cartilage by bone in the diaphysis.

   • Incorrect: The bone model made of hyaline cartilage forms before the bone collar.

2. Formation of bone model made of hyaline cartilage, formation of small cavities and invasion of blood vessels, formation of a bone collar, replacement of cartilage by bone in the diaphysis.

   • Incorrect: The formation of the bone collar occurs before the invasion of blood vessels.

3. Formation of bone model made of hyaline cartilage, formation of a bone collar, formation of small cavities and invasion of blood vessels, replacement of cartilage by bone in the proximal and distal epiphyses.

   • Incorrect: The replacement of cartilage by bone occurs first in the diaphysis, not the epiphyses.

4. Formation of bone model made of hyaline cartilage, formation of a bone collar, formation of small cavities and invasion of blood vessels, replacement of cartilage by bone in the diaphysis.

   • Correct: This option correctly outlines the sequence of events in the development of long bones during the embryonic and fetal stages.

In summary, the correct order of events during the embryonic and fetal stages of long bone development is the formation of a bone model made of hyaline cartilage, followed by the formation of a bone collar, the formation of small cavities and invasion of blood vessels, and finally the replacement of cartilage by bone in the diaphysis.