Questions: What binds to actin at its binding sites, allowing the formation of cross-bridges? Multiple Choice Tropomyosin ATP Myosin Troponin

What binds to actin at its binding sites, allowing the formation of cross-bridges? Multiple Choice Tropomyosin ATP Myosin Troponin
Transcript text: What binds to actin at its binding sites, allowing the formation of cross-bridges? Multiple Choice Tropomyosin ATP Myosin Troponin
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Solution

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The answer is the third one (or C): Myosin.

Explanation for each option:

  • Tropomyosin: This protein blocks the binding sites on actin when the muscle is relaxed, preventing cross-bridge formation.
  • ATP: While ATP is crucial for muscle contraction, it does not bind to actin to form cross-bridges. Instead, ATP binds to myosin, providing the energy needed for the myosin heads to detach from actin and re-cock for another cycle of binding and pulling.
  • Myosin: This is the correct answer. Myosin heads bind to actin at its binding sites, forming cross-bridges that are essential for muscle contraction.
  • Troponin: This protein binds to calcium ions and causes a conformational change that moves tropomyosin away from actin's binding sites, allowing myosin to bind to actin. However, troponin itself does not bind to actin to form cross-bridges.

Summary: Myosin binds to actin at its binding sites, allowing the formation of cross-bridges necessary for muscle contraction.

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