Questions: Question 3 Which of the following is NOT true about Auer rods? They are elongated structures found in the cytoplasm of leukemic blasts They are elongated structures found in the cytoplasm of normal blasts Indicates that the blast is of myeloid origin They are fused primary (azurophilic) granules

The answer is the second one: They are elongated structures found in the cytoplasm of normal blasts.

Explanation for each option:

1. They are elongated structures found in the cytoplasm of leukemic blasts: This statement is true. Auer rods are typically found in the cytoplasm of leukemic blasts, particularly in acute myeloid leukemia (AML).

2. They are elongated structures found in the cytoplasm of normal blasts: This statement is NOT true. Auer rods are not found in normal blasts; they are associated with abnormal, leukemic cells.

3. Indicates that the blast is of myeloid origin: This statement is true. The presence of Auer rods is indicative of myeloid lineage, helping to differentiate myeloid leukemias from lymphoid leukemias.

4. They are fused primary (azurophilic) granules: This statement is true. Auer rods are formed from the fusion of primary granules, which are azurophilic in nature.

In summary, the incorrect statement is that Auer rods are found in the cytoplasm of normal blasts.