Questions: Part D After a power stroke, the myosin head must detach from actin before another power stroke can occur. What causes cross bridge detachment? Calcium ions bind to troponin. Acetylcholine binds to receptors in the junctional folds of the sarcolemma. ATP binds to the myosin head. ADP and inorganic phosphate are bound to the myosin head. Hints Clear all Check answer 8:03 PM 1/5/2025

Part D After a power stroke, the myosin head must detach from actin before another power stroke can occur. What causes cross bridge detachment? Calcium ions bind to troponin. Acetylcholine binds to receptors in the junctional folds of the sarcolemma. ATP binds to the myosin head. ADP and inorganic phosphate are bound to the myosin head. Hints Clear all Check answer 8:03 PM 1/5/2025
Transcript text: Part D After a power stroke, the myosin head must detach from actin before another power stroke can occur. What causes cross bridge detachment? Calcium ions bind to troponin. Acetylcholine binds to receptors in the junctional folds of the sarcolemma. ATP binds to the myosin head. ADP and inorganic phosphate are bound to the myosin head. Hints Clear all Check answer 8:03 PM 1/5/2025
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Solution

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The answer is the third one: ATP binds to the myosin head.

Explanation for each option:

  • Calcium ions bind to troponin: This is incorrect. Calcium ions binding to troponin cause a conformational change that moves tropomyosin away from the binding sites on actin, allowing the myosin head to attach to actin and initiate a power stroke. It does not cause detachment.

  • Acetylcholine binds to receptors in the junctional folds of the sarcolemma: This is incorrect. Acetylcholine binding to its receptors on the sarcolemma initiates an action potential in the muscle fiber, leading to muscle contraction, but it does not directly cause the detachment of the myosin head from actin.

  • ATP binds to the myosin head: This is correct. The binding of ATP to the myosin head causes the myosin head to detach from the actin filament. This is a crucial step in the cross-bridge cycle, allowing the myosin head to reset and prepare for another power stroke.

  • ADP and inorganic phosphate are bound to the myosin head: This is incorrect. The presence of ADP and inorganic phosphate on the myosin head is associated with the power stroke phase, where the myosin head is attached to actin and pulling it. Detachment occurs when ATP binds, not when ADP and inorganic phosphate are present.

In summary, ATP binding to the myosin head is the key event that causes cross-bridge detachment, allowing the cycle of muscle contraction to continue.

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