To simplify the given expression, we need to factor each polynomial in the numerators and denominators. After factoring, we can cancel out any common factors between the numerators and denominators.
We start with the expression:
\[ \frac{X^{2}+4X-5}{X^{2}+3X-10} \cdot \frac{X+3}{X^{2}+2X-3} \]
Factoring each part, we find:
Substituting the factored forms back into the expression gives us:
\[ \frac{(X - 1)(X + 5)}{(X - 2)(X + 5)} \cdot \frac{X + 3}{(X - 1)(X + 3)} \]
Next, we can cancel the common factors in the numerator and denominator:
This simplifies our expression to:
\[ \frac{1}{X - 2} \]
Thus, the simplified expression is:
\[ \boxed{\frac{1}{X - 2}} \]
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