Questions: onsider a protein that is targeted to be excreted to the outside of the plasma membrane. There would this protein be located in the Golgi? in the lumen (inside) of the Golgi embedded as an integral membrane protein in the Golgi membrane outside the Golgi as a peripheral membrane protein

The answer is the first one: in the lumen (inside) of the Golgi.

Explanation:

1. In the lumen (inside) of the Golgi: This is the correct answer. Proteins that are destined to be secreted outside the cell are typically synthesized in the rough endoplasmic reticulum (ER) and then transported to the Golgi apparatus. Within the Golgi, these proteins are processed and modified in the lumen before being packaged into vesicles for exocytosis.

2. Embedded as an integral membrane protein in the Golgi membrane: This option is incorrect because integral membrane proteins are typically those that are meant to reside within the membrane itself, either of the Golgi or another organelle, or the plasma membrane. They are not usually secreted outside the cell.

3. Outside the Golgi as a peripheral membrane protein: This option is incorrect because peripheral membrane proteins are associated with the surface of membranes and are not typically secreted outside the cell. They usually function in signaling or maintaining the cell's shape and structure.

Summary: The protein targeted for excretion to the outside of the plasma membrane would be located in the lumen (inside) of the Golgi apparatus, where it undergoes further processing before being transported out of the cell.