Questions: Introns have been shown to do which of the following? Code for enzymes such as endonucleases or reverse transcriptase Stimulate transcription of specific genes Prevent translation of specific proteins through the introduction of early stop codons Give rise to alternative versions of mRNA sequences from the same gene through alternative splicing Catalyze their own removal from a transcript through self-splicing

Introns have been shown to do which of the following?
Code for enzymes such as endonucleases or reverse transcriptase
Stimulate transcription of specific genes
Prevent translation of specific proteins through the introduction of early stop codons
Give rise to alternative versions of mRNA sequences from the same gene through alternative splicing
Catalyze their own removal from a transcript through self-splicing

Transcript text: Introns have been shown to do which of the following? Code for enzymes such as endonucleases or reverse transcriptase Stimulate transcription of specific genes Prevent translation of specific proteins through the introduction of early stop codons Give rise to alternative versions of mRNA sequences from the same gene through alternative splicing Catalyze their own removal from a transcript through self-splicing

Solution

Solution Steps

Step 1: Analyze the options related to intron function

Introns are non-coding sections of a gene that are transcribed into RNA but removed by splicing before translation. Let's consider each option:

Code for enzymes: Introns are non-coding sequences and thus do not code for enzymes like endonucleases or reverse transcriptase.
Stimulate transcription: Introns may contain regulatory elements that influence transcription, but their primary function isn't to stimulate it.
Prevent translation: This is not a direct function of introns. Stop codons occur within exons (coding sequences), not introns.
Give rise to alternative versions of mRNA: This is a key function of introns. Alternative splicing can create multiple mRNA isoforms from a single gene by including or excluding different exons and introns during splicing.
Catalyze their own removal: Some introns (group I and group II introns) are self-splicing ribozymes, meaning they catalyze their own removal.

Step 2: Identify the correct options

Based on the analysis above, the correct options are:

Give rise to alternative versions of mRNA sequences from the same gene through alternative splicing
Catalyze their own removal from a transcript through self-splicing

Final Answer:

Introns have been shown to: give rise to alternative versions of mRNA sequences from the same gene through alternative splicing, and catalyze their own removal from a transcript through self-splicing.

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