Questions: Which of the following is true about human sex chromosomes? They are always heterogametic They act like homologous chromosomes during meiosis so each gamete will get one sex chromosome. They do not participate in meiosis. They have the same gene configuration and same loci. They are independent during meiosis.

The answer is the second one: They act like homologous chromosomes during meiosis so each gamete will get one sex chromosome.

Explanation for each option:

1. They are always heterogametic: This is incorrect. In humans, males are heterogametic (XY), but females are homogametic (XX).

2. They act like homologous chromosomes during meiosis so each gamete will get one sex chromosome: This is correct. During meiosis, sex chromosomes pair up and segregate so that each gamete receives one sex chromosome, ensuring that offspring have the correct number of sex chromosomes.

3. They do not participate in meiosis: This is incorrect. Sex chromosomes do participate in meiosis, just like autosomes, to ensure proper distribution to gametes.

4. They have the same gene configuration and same loci: This is incorrect. The X and Y chromosomes have different gene configurations and loci, although they share some regions of homology.

5. They are independent during meiosis: This is incorrect. Sex chromosomes pair and segregate during meiosis, so they are not independent.

In summary, the correct statement about human sex chromosomes is that they act like homologous chromosomes during meiosis so each gamete will get one sex chromosome.