Questions: The federal government first became heavily involved in the daily lives of Americans through the New Deal programs of President Franklin Roosevelt, which were in response to which situation?

The answer is the Great Depression.

While regional conflicts have occurred throughout U.S. history, they were not the primary reason for the New Deal programs. The New Deal was specifically designed to address economic issues on a national scale rather than regional conflicts.

The Great Depression was a severe worldwide economic downturn that took place during the 1930s. It led to widespread unemployment, poverty, and economic instability in the United States. In response, President Franklin D. Roosevelt implemented the New Deal programs to provide relief, recovery, and reform to the American economy. These programs marked a significant increase in the federal government's involvement in the daily lives of Americans, aiming to alleviate the effects of the Great Depression.

World War II began in 1939 and the United States entered the war in 1941. While the war had significant economic and social impacts, the New Deal programs were initiated in the 1930s, prior to the U.S. involvement in World War II. Therefore, the New Deal was not a response to World War II.