Questions: Lyme disease is an example of a disease that is due to increased interaction between humans and tick-carrying animals.

The answer is the first one: increased interaction between humans and tick-carrying animals.

Explanation for each option:

1. Increased interaction between humans and tick-carrying animals: Correct. Lyme disease is caused by the bacterium Borrelia burgdorferi, which is transmitted to humans through the bite of infected black-legged ticks. Increased interaction with tick habitats, such as wooded or grassy areas, raises the risk of contracting Lyme disease.

2. Failure to effectively vaccinate children: Incorrect. There is currently no widely used vaccine for Lyme disease in humans. Vaccination is not a factor in the spread of Lyme disease.

3. A mutation in the human genome: Incorrect. Lyme disease is an infectious disease caused by a bacterium, not a genetic disorder resulting from a mutation in the human genome.

4. Climate change leading to a significantly greater mosquito population: Incorrect. While climate change can affect the distribution of various vector-borne diseases, Lyme disease is specifically transmitted by ticks, not mosquitoes.

5. An increase in the number of people traveling to Asia and Africa: Incorrect. Lyme disease is most commonly found in North America and Europe. Increased travel to Asia and Africa is not a significant factor in the spread of Lyme disease.

Summary: Lyme disease is primarily due to increased interaction between humans and tick-carrying animals.