The answer is the third one (or C): the T-cell count is less than 200.
Explanation for each option:
a. A person tests positive for HIV antibodies: This indicates that the person has been infected with HIV, but it does not necessarily mean they have progressed to AIDS. HIV infection can remain in a latent phase for many years before progressing to AIDS.
b. The person develops a severe, life-threatening disease: While the development of severe, life-threatening opportunistic infections or cancers is a hallmark of AIDS, the diagnosis of AIDS is specifically tied to the T-cell count, not just the presence of these diseases.
c. The T-cell count is less than 200: This is the correct answer. AIDS (Acquired Immunodeficiency Syndrome) is diagnosed when the CD4 T-cell count drops below 200 cells per cubic millimeter of blood. This low count indicates a severely weakened immune system, making the person susceptible to opportunistic infections and certain cancers.
d. The B-cell count is less than 200: B-cells are a type of white blood cell involved in producing antibodies. While B-cells are important for the immune response, the diagnosis of AIDS is not based on B-cell count but rather on the CD4 T-cell count.
Summary:
AIDS is diagnosed when the T-cell count is less than 200 cells per cubic millimeter of blood, indicating a severely compromised immune system.