Questions: The nitroblue-tetrazolium (NBT) test is the primary test for chronic granulomatous disease. In this test, first NBT is added to cells. NADPH oxidase then takes an electron from NADPH and donates it to NBT. When NBT receives an electron, it forms an insoluble blue compound (formazan). Based on this information, is NBT oxidized or reduced? (NCLEX-HESI-TEAS Style) View Available Hint(s) NBT is reduced. NBT is oxidized.

The nitroblue-tetrazolium (NBT) test is the primary test for chronic granulomatous disease. In this test, first NBT is added to cells. NADPH oxidase then takes an electron from NADPH and donates it to NBT. When NBT receives an electron, it forms an insoluble blue compound (formazan). Based on this information, is NBT oxidized or reduced? (NCLEX-HESI-TEAS Style) View Available Hint(s) NBT is reduced. NBT is oxidized.
Transcript text: The nitroblue-tetrazolium (NBT) test is the primary test for chronic granulomatous disease. In this test, first NBT is added to cells. NADPH oxidase then takes an electron from NADPH and donates it to NBT. When NBT receives an electron, it forms an insoluble blue compound (formazan). Based on this information, is NBT oxidized or reduced? (NCLEX-HESI-TEAS Style) View Available Hint(s) NBT is reduced. NBT is oxidized.
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Solution

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Solution Steps

Step 1: Understanding the Reaction Process

In the NBT test, NADPH oxidase transfers an electron from NADPH to NBT. This electron transfer is a key part of the reaction process.

Step 2: Identifying Oxidation and Reduction

In a redox reaction, the substance that gains electrons is reduced, while the substance that loses electrons is oxidized. Here, NBT receives an electron.

Step 3: Determining the State of NBT

Since NBT receives an electron, it undergoes reduction. The formation of the insoluble blue compound (formazan) indicates that NBT has been reduced.

Final Answer

\(\boxed{\text{NBT is reduced.}}\)

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