Questions: Suppose a student determines that their genotype is D1S8O12,26. Does this mean that both mom and dad must also be D1S8012,26? Explain your answer. Suppose a student determines that their genotype is D1S80O12,26. Does this mean that all their siblings must have at least ONE D1S80 12 or D1S8026 allele? Explain your answer.

2. The answer is no, both mom and dad do not have to be D1S80 12,26.

Explanation: The genotype D1S80 12,26 indicates that the student has one allele with 12 repeats and another with 26 repeats at the D1S80 locus. This does not mean that both parents must have the exact same genotype. Instead, it means that one parent must have contributed the allele with 12 repeats and the other parent must have contributed the allele with 26 repeats. Each parent could have a variety of genotypes that include these alleles. For example, one parent could be D1S80 12,12 and the other could be D1S80 26,26, or one could be D1S80 12,26 and the other D1S80 26,30, among other possibilities.

3. The answer is yes, all their siblings must have at least one D1S80 12 or D1S80 26 allele.

Explanation: The student has a genotype of D1S80 12,26, meaning they received one allele with 12 repeats from one parent and one allele with 26 repeats from the other parent. Since these alleles are present in the parents, any sibling must inherit one allele from each parent as well. Therefore, each sibling must have at least one of the alleles present in the parents, which are the 12 or 26 repeats. However, the siblings could have different combinations of these alleles, such as 12,12; 12,26; 26,26; or even other alleles if the parents have more than these two alleles.