Questions: A physician orders metformin 1 g bid for a patient newly diagnosed with type 2 diabetes mellitus. A new stock bottle of 500 metformin 500 mg tablets is used. - How many tablets remain in the stock bottle after the prescription is filled?

To determine how many tablets remain in the stock bottle after the prescription is filled, we need to follow these steps:

1. Understand the Prescription: The physician has ordered metformin 1 g (1000 mg) to be taken twice a day (bid). This means the patient needs 1000 mg per dose, and since each tablet is 500 mg, the patient will need 2 tablets per dose.

2. Calculate Daily Requirement: Since the patient takes the medication twice a day, they will need 2 tablets per dose x 2 doses per day = 4 tablets per day.

3. Determine the Duration of the Prescription: The problem does not specify the duration for which the prescription is written. However, for the purpose of this calculation, let's assume a common prescription duration of 30 days.

4. Calculate Total Tablets Needed: For a 30-day supply, the patient will need 4 tablets per day x 30 days = 120 tablets.

5. Calculate Remaining Tablets: The stock bottle initially contains 500 tablets. After dispensing 120 tablets, the remaining number of tablets in the stock bottle will be 500 - 120 = 380 tablets.

Therefore, the answer is: 380 tablets remain in the stock bottle after the prescription is filled.