Questions: Part A is a progressive degenerative disease of the basal nuclei that affects the dopamine-secreting pathways. Huntington's disease Parkinson's disease Alzheimer's disease mad cow disease

Part A is a progressive degenerative disease of the basal nuclei that affects the dopamine-secreting pathways. Huntington's disease Parkinson's disease Alzheimer's disease mad cow disease
Transcript text: Part A $\qquad$ is a progressive degenerative disease of the basal nuclei that affects the dopamine-secreting pathways. Huntington's disease Parkinson's disease Alzheimer's disease mad cow disease
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Solution

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The answer is the second one: Parkinson's disease.

Explanation for each option:

  1. Huntington's disease: This is a genetic disorder that causes the progressive breakdown of nerve cells in the brain, but it primarily affects different areas than the basal nuclei and is not specifically related to dopamine-secreting pathways.

  2. Parkinson's disease: This is a progressive degenerative disease of the basal nuclei that specifically affects the dopamine-secreting pathways. It is characterized by symptoms such as tremors, stiffness, and bradykinesia (slowness of movement).

  3. Alzheimer's disease: This is a progressive neurodegenerative disease that primarily affects memory and cognitive function, and it is not specifically related to the basal nuclei or dopamine pathways.

  4. Mad cow disease: Also known as bovine spongiform encephalopathy (BSE), this is a neurodegenerative disease in cattle that can affect humans (as variant Creutzfeldt-Jakob disease), but it is not related to the basal nuclei or dopamine pathways.

In summary, Parkinson's disease is the correct answer as it directly involves the degeneration of dopamine-secreting pathways in the basal nuclei.

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