We start with the expression:
\[ \frac{27!}{22!} \]
To simplify this, we can cancel out the common factorial terms. This gives us:
\[ \frac{27!}{22!} = 27 \times 26 \times 25 \times 24 \times 23 \]
Now, we calculate the product of the descending integers from 27 to 23:
\[ 27 \times 26 = 702 \] \[ 702 \times 25 = 17550 \] \[ 17550 \times 24 = 421200 \] \[ 421200 \times 23 = 9687600 \]
Thus, the value of the expression is:
\[ \boxed{9687600} \]
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