First, we calculate the base value: \[ -2.0 \times 10^{6} = -2000000.0 \]
Next, we raise the base to the power of 4: \[ \left(-2000000.0\right)^{4} = 1.6 \times 10^{25} \]
Finally, we express the result in scientific notation: \[ 1.60 \times 10^{25} \]
\(\boxed{1.60 \times 10^{25}}\)
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