The answer is the last one: Muscle atrophy with weakness and decreased coordination.
Explanation for each option:
A) Double vision - This is not typically associated with Duchenne muscular dystrophy (DMD). DMD primarily affects skeletal muscles, leading to muscle weakness and atrophy, rather than issues with vision.
B) Bradykinesia, rigidity, and tremor - These symptoms are more characteristic of Parkinson's disease, which affects the nervous system, rather than DMD, which is a muscular disorder.
C) Spasticity and hypertonic reflexes - These symptoms are more commonly associated with conditions affecting the central nervous system, such as cerebral palsy or multiple sclerosis, rather than DMD.
Muscle atrophy with weakness and decreased coordination - This is the correct answer. DMD is characterized by progressive muscle weakness and degeneration, leading to muscle atrophy and decreased coordination as the disease progresses.
Summary: In a child diagnosed with Duchenne muscular dystrophy, early signs of disease progression include muscle atrophy, weakness, and decreased coordination.