Questions: Which diagnostic test can detect destruction of circulating platelets as the cause of thrombocytopenia? O Hemoglobin O Bone marrow analysis O Prothrombin time (PT) O Peripheral blood smear Confident Not Sure

Which diagnostic test can detect destruction of circulating platelets as the cause of thrombocytopenia? O Hemoglobin O Bone marrow analysis O Prothrombin time (PT) O Peripheral blood smear Confident Not Sure
Transcript text: Which diagnostic test can detect destruction of circulating platelets as the cause of thrombocytopenia? O Hemoglobin O Bone marrow analysis O Prothrombin time (PT) O Peripheral blood smear Confident Not Sure
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Solution

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The answer is the fourth one: Peripheral blood smear.

Explanation for each option:

  1. Hemoglobin: This test measures the amount of hemoglobin in the blood and is used to assess anemia, not thrombocytopenia or platelet destruction. Therefore, it is not the correct test for detecting destruction of circulating platelets.

  2. Bone marrow analysis: This test examines the bone marrow to assess the production of blood cells, including platelets. While it can help determine if the bone marrow is producing enough platelets, it does not directly detect the destruction of circulating platelets.

  3. Prothrombin time (PT): This test measures how long it takes blood to clot and is used to evaluate the blood's ability to clot properly. It is not used to detect platelet destruction.

  4. Peripheral blood smear: This test involves examining a sample of blood under a microscope to look at the size, shape, and number of blood cells, including platelets. It can help identify abnormalities in platelets and may show evidence of platelet destruction, such as the presence of schistocytes (fragmented red blood cells) or other signs of platelet consumption.

In summary, a peripheral blood smear is the most appropriate test to detect the destruction of circulating platelets as the cause of thrombocytopenia.

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