Questions: Rank the following in order of increasing leaving group ability, putting the worst leaving group first.
H2O
HO^-
NH3
H2N^-
I
II
III
IV
Multiple Choice
IV < II < III < I
III < IV < I < II
Transcript text: Chapter 7 Quiz i
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Rank the following in order of increasing leaving group ability, putting the worst leaving group first.
18
$\mathrm{H}_{2} \mathrm{O}$
$\mathrm{HO}^{-}$
$\mathrm{NH}_{3}$
$\mathrm{H}_{2} \mathrm{~N}^{-}$
I
II
III
IV
Multiple Choice
IV $<$ II $<$ III $<$ I
\[
\text { III }<\text { IV }<\text { I }<\text { II }
\]
Solution
Solution Steps
Step 1: Understand Leaving Group Ability
Leaving group ability is determined by the stability of the group after it leaves. A good leaving group is stable on its own, often as a weak base. The weaker the base, the better the leaving group.
Step 2: Analyze Each Group
$\mathrm{HO}^{-}$: Hydroxide ion is a strong base and thus a poor leaving group.
$\mathrm{H}_{2} \mathrm{~N}^{-}$: Amide ion is an even stronger base than hydroxide, making it a worse leaving group.
$\mathrm{NH}_{3}$: Ammonia is a weak base and a better leaving group than hydroxide.
$\mathrm{H}_{2} \mathrm{O}$: Water is a very weak base and a good leaving group.
Step 3: Rank the Groups
Rank the groups from worst to best leaving group ability: